# Methodology — Neuroinflammation

## Included biomarkers
- CSF: Ab42, total tau, pTau181, NfL, YKL-40
- Plasma: NfL, pTau217, GFAP

## Neuroimaging
- Structural MRI: cortical volumes (FreeSurfer)
- Amyloid/tau PET: Centiloid scale
- DTI: FA, MD of white matter tracts

## Clinical scales
- Alzheimer: CDR, MMSE, MoCA
- Parkinson: UPDRS-III
- MS: EDSS
